Suspended polyhydroxyalkanoate microspheres as 3D carriers for mammalian cell growth

Nanofibrous polyhydroxyalkanoate matrices as cell growth supporting materials.

Polyhydroxyalkanoates (PHAs) have been demonstrated to be a family of biopolymers with good biodegradability and biocompatibility. To mimic the real microenvironment of extracellular matrix (ECM) for cell growth, novel nanofiber matrices based on PHA polymers were prepared via a phase separation process. Three-dimensional interconnected fibrous networks were observed in these matrices with aver...

Preparation of Biodegradable Microspheres Useful as Carriers for Macromolecules

Nanofibrous hollow microspheres self-assembled from star-shaped polymers as injectable cell carriers for knee repair

To repair complexly shaped tissue defects, an injectable cell carrier is desirable to achieve an accurate fit and to minimize surgical intervention. However, the injectable carriers available at present have limitations, and are not used clinically for cartilage regeneration. Here, we report nanofibrous hollow microspheres self-assembled from star-shaped biodegradable polymers as an injectable ...

Application of Chitosan Microspheres as Drug Carriers : a Review

Rahul Nair*, B.Haritha Reddy C.K.Ashok Kumar, K.Jayraj Kumar. 1.Sree Vidyanikethan College of Pharmacy, A.Rangampet, Chittoor District Tirupathi, Andhra Pradesh. 2. D.R.Karigowda College of Pharmacy Hassan. Karnataka. ______________________________________________________________________________________ ABSTRACT Chitosan (CS) is a naturally occurring polymer which finds a wide array of pharmace...

Preparation and properties of polyhydroxybutyrate microspheres as drug carriers

Designing of controlled-release drug delivery systems is a promising and rapidly developing line of pharmacology. The main advantage of using drug delivery systems is that drug concentration in a patient’s blood and/or tissues can be maintained at a target level for an extended time (Kost 2001). The principal requirement for fabricating prolonged-action controlled-release drug delivery systems ...